There are many regions to choose from, each rich in history, art & architecture, culture and gastronomy.
France is also the largest market for motorcycles and scooters. In 2015 roughly 250,000 new units were sold outpacing neighboring countries by a wide margin. The locals are used to seeing motorcycles and giving them due respect.
The wealth of a secondary road network of motorcycle friendly roads must help sales and attract motorcyclists. No need to ride on endless stretches of highway straightaways.
With villages dating back to the Roman empire and earlier, there are plenty of vestiges such as amphitheaters, roads, aqua ducts, bridges, fortified towns to see along your route. If you are looking for something earlier, there caves adorned with primitive art over 20,000 years old.
If you prefer something a little more recent, the Chateaux of the Loire Valley are architectural masterpieces of a bygone era. Or perhaps you want to visit vestiges of WW II, Napoleon, the Knights Templar, Leonardo da Vinci, Nostradamus, Louis XIV, and more can be found along your route.